When we speak, we use sounds that belong to the system of a particular language (phonology) to form words that convey our intended meaning (semantics). We string them together in a particular order (grammar) to convey the message that we want to communicate in a conversation (discourse). Impairments in language production and comprehension at each of these levels are caused by disease found in individuals with Frontotemporal degeneration (FTD). Different regions of the brain are associated with different aspects of language, and the effects of different forms of FTD on these parts of the brain thus can interfere with comprehension and expression. The techniques employed to study language involve asking subjects to speak and to understand in a broad range of tasks, such as repeating words, answering questions about the meaning of a sentence, or telling a story from a series of pictures. Language-oriented tasks can also be conducted in conjunction with neuroimaging studies to investigate the regions involved in each specific aspect of language functioning.